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Human Technopole (HT) is a research organisation based in Milan (Italy) with a focus on human biology in health and disease. HT is an independent foundation created and supported by the Italian government that consists of several Research Centres. The Centres will work together to enable collaborative, interdisciplinary research and to create an open, collaborative environment that will help promote life science research both nationally and internationally.

We are seeking talented early career researchers to establish their independent laboratory at the HT Research Centre for Structural Biology.

The Research Group Leaders will be responsible for developing an independent scientific programme within the Centre, as well as contributing to the collegial development of the HT research programme. They will be active researchers carrying out high-quality, internationally competitive research and contributors to the international scientific community. The HT Research Centre for Structural Biology will offer an outstanding infrastructure for carrying out modern EM workflows, including SPA, cryo-FIB-SEM, CLEM and cryo- and room temperature-tomography. Additionally, state-of-the art equipment for biochemical and biophysical characterization of macromolecular complexes will be available, as well as a large-scale cell culture facility, including large fermenters for microorganisms and bioreactors for mammalian cells. In the spirit of the HT, the Research Group Leaders will have access to additional facilities, such as the Light Microscopy Facility, that are formally associated to the other HT Centres. Newly appointed Research Group Leaders will be offered a generous start-up package and core funding. A strategic priority is represented by individuals with experience and an active research program employing cryo-FIB-SEM approaches.

Key tasks and responsibilities

The Research Group Leader will:

  • Develop and supervise the establishment of a world-class research programme in structural cell biology;
  • Lead their own research group;
  • Foster a diverse and nurturing research environment through leading and mentoring members of their teams;
  • Build effective links and collaborations within other HT research investigators;
  • Develop and foster links between HT and other national and international research organizations;
  • Contribute to the preparation of Centre reports to be reviewed by an external expert board;
  • Actively participate in initiatives that pursue improvement of all aspects of HT;
  • Actively participate in the co-organization and implementation of activities that will promote the image of HT in the international structural biology community, such as symposia and workshops;
  • Contribute to the establishment of a collaborative and open scientific environment by actively participating in meetings and seminar series internal to HT. This will foster synergies between the groups and propagation of knowledge;
  • Raise third-party funding;
  • Participate and helping to designing HT Core Facilities.

Key requirements

The selected candidates will have an outstanding record in Structural Biology, in particular in cryo-electron microscopy workflows, and an interest, that can be non-exclusive, in the analysis of human systems and diseases. The Centre for Structural Biology will work closely with other HT Research Centres to achieve synergies and reach joint goals. The selected candidates will possess scientific vision, leadership skills and be competitive in acquiring extramural grants. Basic requirements for the position include a PhD in a relevant science subject, and a proven record of scientific research output in the field of structural biology. Excellent organisational skills and a fluent command of English are essential.

Additional Information

The Research Group leader will be based in Milan, recently named the city with the best quality of life in Italy https://lab24.ilsole24ore.com/qualita-della-vita-2019/.

HT offers a highly collaborative, international culture. The working language at HT will be English. HT will foster top quality, interdisciplinary research by promoting a vibrant environment consisting of independent research groups with access to outstanding graduate students, postdoctoral fellows and core facilities.

HT is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to a leading, internationally competitive, research organization and seeks to promote a collegial and open atmosphere. The compensation package granted will be internationally competitive and comprise pension scheme, medical and other social benefits and support for relocation and installation.

Application Instructions

Please apply only through the dedicated area below (Apply now), sending a CV, a motivation letter, a project description in English and providing contacts for four potential referees.

The project description should be a maximum of 8 pages long and include both a short description of current and future research in the group in the context of HT.

Questions concerning the role and any queries regarding the terms and conditions should be sent to the Head of the HT Structural Biology Research Centre, Alessandro Vannini at alessandro.vannini@fht.org.

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